The Serb stroked in the rebound from a Graziano Pelle shot that struck the post to give the Saints a first league win away against the Red Devils for 17 years
Dusan Tadic was the hero as Southampton claimed their first league victory over Manchester United at Old Trafford since 1988 and strengthened their position in the top four.
Tadic slotted in the rebound from a Graziano Pelle shot that struck the post on 69 minutes to give the Saints the lead in a game United had dominated.
The hosts rallied but were unable to muster a single shot on target for the entirety of the match, with Juan Mata missing two gilt-edged opportunities to secure them a point.
Ronald Koeman – widely documented to have a frosty relationship with opposite number Louis van Gaal following disagreements during their time at Barcelona and Ajax – saw his side avenge their 2-1 defeat when the teams met at St Mary’s Stadium last month.
The injury-enforced withdrawal of Toby Alderweireld was the only low point for Southampton, while Van Gaal has work to do to rediscover his side’s finishing touch if they are to regain third place.
Nathaniel Clyne – back in the Saints’ starting XI for the first time since Boxing Day – went close inside two minutes as he dragged a shot wide before Di Maria’s inviting cross failed to find a touch from any United team-mates.
Like Clyne, Alderweireld was also returning for the visitors, having not featured in the FA Cup draw with Ipswich Town, but the Belgian was forced off injured inside 20 minutes and replaced by Florin Gardos.
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